1290543-63-3 Nirogacestat

Propjetajiet:

Dehra bajda għal trab abjad barra

Punt tat-togħlija: 651.3 ± 55. 0 grad
Densità 1.16 ± 0. 1 g \/ cm3

Applikazzjoni:

Nirogacetat jintuża prinċipalment biex jikkura pazjenti adulti b'fibroadenoma progressiva li jeħtieġu trattament sistemiku. Nirogacetat huwa inibitur orali gamma secretase li jinibixxi l-attività ta 'gamma secretase, jinterferixxi ma' mogħdijiet ta 'sinjalazzjoni ċellulari, u b'hekk irażżan it-tkabbir u l-proliferazzjoni taċ-ċelloli tat-tumur.
 

Sinonimi:

Nirogacestat

1290543-63-3

Ogsiveo

Nirogacestatum

(S)-2-(((S)-6,8-Difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-({{1 0}} (2- methyl -1- (neopentylamino) propan -2- yl) -1 h-imidazol -4-}}}} yl) pentanamide

(2s) -2- [[(2s) -6, 8- difluoro -1, 2,3, {4- tetrahydronaphthalen {-2- yl] yl] amino]-[{{12} } [1- (2, 2- dimethylpropylamino) -2- methylPopan -2- yl] imidazol -4-}} yl] pentanamide

2- (5, 7- difluoro -1, 2,3, {4- Tetrahydronaphthalen {-3- ylamino) -n - ({1- ({{{{{{{{{{{{{{{{{{{{{{{{{{{{{{{ 11}} methyl -1- (neopentylamino) propan -2- yl) -1 h-imidazol -4- yl) pentanamide

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